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  6. Melanoma with Decision DX Cutaneous Melanoma Database

Melanoma with Decision DX Cutaneous Melanoma Database

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Access the Database

To request access this specialized database, you must already have access to the latest SEER Reasearch Plus Data.

  • If you do not have access to SEER Research Plus Data, first request Access to the SEER data.
  • If you already have access, use the request options below.

Required Information:

  • Contact Information
  • SEER*Stat Username
  • Purpose and Analysis Plan

Submit a Request

This database is available only to U.S. based researchers affiliated with U.S. institutions.

The database includes Decision DX Cutaneous Melanoma (CM)-related data fields for skin melanoma cases. These data were obtained through a linkage of CM cases (morphology codes 8720-8790) from the SEER registries to Decision DX CM test results provided by Castle Biosciences. The Alaska Native Tumor Registry did not participate in the linkage. Details about the linkage methods can be found in a recent journal article (1). Approximately 562,000 CM cases diagnosed from 2013 to 2019 were included in the linkage, of which 16,518 cases were linked to Decision DX CM test results.

Approximately 1,629,000 invasive breast cancer cases were included in the linkage, of which 364,292 were linked to Oncotype DX RS test orders and results.

Variable Definitions

The specialized Decision DX CM fields are described below.

Variable Name in SEER*Stat Values Description
DecisionDX CM Main Risk Class
  1. Class 1
  2. Class 2
 Categorization of risk class
DecisionDX CM Risk Subclass
  1. Class 1A
  2. Class 1B
  3. Class 2A
  4. Class 2B
 Categorization of risk subclass
DecisionDX CM Test Report Date Year 2013+ Year in which the test was performed
DecisionDX CM Test Report Date Month Jan-Dec Month in which the test was reported; Not available in case listing
DecisionDX CM Months since Diagnosis

0+

 Number of months between diagnosis and test report dates

Database Details

There is currently one Decision DX Cutaneous Melanoma Database available to approved requesters. It is identical to the SEER Research Plus database other than the specialized fields described above.

17 Registries (excl AK)

  • Available in Frequency, Survival and Case listing sessions in SEER*Stat.
  • November 2023 data submission with all tumor records from 2001 to 2021 for the included registries, but the Decision DX CM fields are available for tested patients diagnosed from 2013 to 2019.
  • It does not include Alaska Native Tumor Registry Data.
  • The number of patients with at least one linked test result is 9,641 patients/9,698 tumors.

Several additional versions of this database will become available soon (e.g., including SEER 22 registries as well as versions with census tract attributes. Some of these additional databases may require IRB approval. Periodic linkages have been conducted to update the database).

Data Limitations and Analytical Considerations

The SEER treatment data is limited to the first course of treatment, therefore it does not have the full sequence of treatments (refer to the Treatment Data Limitations for more information).

Reference

  1. Petkov VI, Byun JS, Ward KC, Schussler NC, Archer NP, Bentler S, Doherty JA, Durbin EB, Gershman ST, Cheng I, Insaf T, Gonsalves L, Hernandez BY, Koch L, Liu L, Monnereau A, Morawski BM, Schwartz SM, Stroup A, Wiggins C, Wu XC, Bonds S, Negoita S, Penberthy L. Reporting tumor genomic test results to SEER registries via linkages. J Natl Cancer Inst Monogr. 2024 Aug 1;2024(65):168-179. [PubMed Abstract]