Name

17-Ketosteroids

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Definition

17-ketosteroids are substances that form when the body breaks down male steroid sex hormones called androgens and other hormones released by the adrenal glands in males and females, and by the testes in males.

Increased levels of 17-ketosteroids may be due to:
- Adrenal glands making too much of their hormones (Cushing syndrome)
- Imbalance of sex hormones in females (polycystic ovary syndrome)
- Ovarian cancer
- Testicular cancer
- Overactive thyroid
- Obesity
- Stress
- Testicular cancer

Decreased levels of 17-ketosteroids may be due to:
- Adrenal glands not making enough of their hormones (Addison disease)
- Kidney damage
- Pituitary gland not making enough of its hormones (hypopituitarism)
- Removal of the testicles (castration)

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